HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 216
+	Hs
		900494 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		RAB35_HUMAN (6-188): 1.31e-87: 258: 29.19
+	Hs
		925294 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		RAB35_HUMAN (6-188): 1.31e-87: 258: 29.19
+	Hs
		900355 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		RAB1A_HUMAN (1-196): 3.67e-82: 244: 28.00
+	Hs
		918847 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		RAB1A_HUMAN (1-196): 3.67e-82: 244: 28.00
+	Hs
		436244 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		RAB1A_HUMAN (1-196): 3.67e-82: 244: 28.00
+	Hs
		900882 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		RAB1B_HUMAN (4-195): 1.12e-80: 240: 28.72
+	Hs
		925600 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		RAB1B_HUMAN (4-195): 1.12e-80: 240: 28.72
+	Hs
		894710 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		RAB8A_HUMAN (1-203): 1.27e-79: 238: 24.76
+	Hs
		436498 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		RAB1B_HUMAN (4-195): 1.12e-80: 240: 28.72
+	Hs
		894716 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		RAB8A_HUMAN (1-203): 1.27e-79: 238: 24.76
+	Hs
		918849 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		RAB1A_HUMAN (1-196): 3.67e-82: 244: 28.00
+	Hs
		919032 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		436230 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		RAB8A_HUMAN (1-203): 1.27e-79: 238: 24.76
+	Hs
		913995 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		RB11A_HUMAN (4-207): 7.68e-78: 234: 25.94
+	Hs
		894720 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		RAB8A_HUMAN (1-203): 1.27e-79: 238: 24.76
+	Hs
		844856 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13
+	Hs
		844863 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13
+	Hs
		436210 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13
+	Hs
		844872 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13
+	Hs
		591792 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		RAB4A_HUMAN (11-169): 1.53e-27: 105: 34.57