HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 165
+	Hs
		900356 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		923633 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		901053 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		PPIE_HUMAN (2-163): 2.08e-88: 262: 67.28
+	Hs
		673675 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		PPIF_HUMAN (3-164): 6.26e-92: 267: 76.54
+	Hs
		923641 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		893876 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		545308 RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		915585 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		892306 RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00