HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: SWAHC (Q53LP3)
Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C)
Gene: SOWAHC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 525
+	Hs
		900544 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		925328 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		951048 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		894087 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		900423 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		925238 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		925204 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		ANK2_HUMAN (260-522): 2.09e-37: 150: 14.77
+	Hs
		276162 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		PSD10_HUMAN (275-408): 8.79e-40: 145: 26.12
+	Hs
		950953 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		893947 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		900638 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		ANS1B_HUMAN (266-509): 1.16e-33: 138: 15.36
+	Hs
		901042 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		925723 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		436568 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		951454 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		894580 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		545696 RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		900439 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29
+	Hs
		925249 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29
+	Hs
		893969 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29