HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.80	0.716

Property	Details
Experiments	19701800, 36192543
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 728
+	Hs
		900726 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		PARD3_HUMAN (247-554): 1.39e-32: 137: 20.96
+	Hs
		925463 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		PARD3_HUMAN (247-554): 1.39e-32: 137: 20.96
+	Hs
		436425 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		PARD3_HUMAN (247-554): 1.39e-32: 137: 20.96
+	Hs
		900424 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		DLG1_HUMAN (354-728): 3.16e-29: 126: 16.15
+	Hs
		925239 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		DLG1_HUMAN (354-728): 3.16e-29: 126: 16.15
+	Hs
		436278 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		DLG1_HUMAN (354-728): 3.16e-29: 126: 16.15
+	Hs
		950954 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		DLG1_HUMAN (354-728): 3.16e-29: 126: 16.15
+	Hs
		900421 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		PTN13_HUMAN (455-725): 4.02e-23: 107: 15.44
+	Hs
		925236 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		PTN13_HUMAN (455-725): 4.02e-23: 107: 15.44
+	Hs
		436277 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		PTN13_HUMAN (455-725): 4.02e-23: 107: 15.44
+	Mm
		925797 RAC1_MOUSE (1-193): 7.23e-81: 240: 57.22		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Hs
		900710 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		INADL_HUMAN (261-396): 1.13e-15: 83.6: 21.74
+	Hs
		900463 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52
+	Hs
		925273 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52
+	Hs
		900762 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		DLG3_HUMAN (619-713): 1.3e-14: 79.7: 28.87
+	Hs
		436297 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52
+	Hs
		950989 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52
+	Hs
		900727 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		PAR3L_HUMAN (465-724): 7.39e-13: 74.3: 27.90
+	Hs
		436426 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		PAR3L_HUMAN (465-724): 7.39e-13: 74.3: 27.90
+	Hs
		925777 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		USH1C_HUMAN (130-362): 1.57e-11: 69.3: 13.08