HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1356
+	Hs
		900726 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		925463 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		900727 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37
+	Hs
		436426 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37
+	Hs
		901043 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36
+	Hs
		925725 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36
+	Hs
		436569 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36
+	Hs
		900762 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		DLG3_HUMAN (556-1119): 1.21e-27: 123: 13.01
+	Mm
		925797 RAC1_MOUSE (1-193): 7.23e-81: 240: 57.22		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Hs
		900421 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		900820 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Hs
		925236 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		925536 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Hs
		436277 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		900710 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14
+	Hs
		436419 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		900411 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		900463 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		925273 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		436297 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75