HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	31871319, 34315543
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras, RA~Ras
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 541
+	Hs
		925441 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		SNX31_HUMAN (173-541): 1.77e-128: 384: 22.06
+	Hs
		894023 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		SNX17_HUMAN (162-535): 9.12e-108: 331: 25.31
+	Hs
		901043 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43
+	Hs
		925725 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43
+	Hs
		436569 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43
+	Hs
		951455 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43
+	Hs
		894581 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43
+	Hs
		545697 RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12		NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43
+	Mm
		1164086 RHOA_MOUSE (1-193): 7.11e-82: 242: 92.23		NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98
+	Mm
		925799 RAC1_MOUSE (1-193): 7.23e-81: 240: 57.22		NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98
+	Hs
		894342 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		NEB2_HUMAN (40-314): 3.95e-34: 139: 17.98
+	Mm
		892727 CDC42_MOUSE (1-193): 7.44e-78: 232: 51.30		NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98
+	Hs
		158270 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		LIN7A_HUMAN (35-137): 4.69e-29: 116: 33.65
+	Mm
		1116148 RHOA_MOUSE (1-193): 7.11e-82: 242: 92.23		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Mm
		925790 RAC1_MOUSE (1-193): 7.23e-81: 240: 57.22		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Hs
		900820 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		MAGI1_HUMAN (2-334): 3.18e-13: 74.9: 17.51
+	Hs
		925536 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		MAGI1_HUMAN (2-334): 3.18e-13: 74.9: 17.51
+	Hs
		900411 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		ZO1_HUMAN (4-254): 7.48e-12: 70.3: 13.97
+	Hs
		894333 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		MAGI1_HUMAN (2-334): 3.18e-13: 74.9: 17.51
+	Hs
		893933 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		ZO1_HUMAN (4-254): 7.48e-12: 70.3: 13.97