HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: ERBIN (Q96RT1)
Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2)
Gene: ERBIN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 1412
+	Hs
		900824 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		925539 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		951251 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		894337 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		545571 RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		915909 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		892548 RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		900463 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		925273 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		436297 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		950989 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		893999 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		545370 RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		915673 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		892367 RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		915930 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		LRRC1_HUMAN (311-709): 1.39e-23: 108: 15.97
+	Dm
		776889 RAC1_DROME (1-193): 2.47e-78: 233: 54.12		SCRIB_DROME (1095-1408): 4.08e-16: 86.8: 16.82