HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: CEP89 (Q96ST8)
Centrosomal protein of 89 kDa (Cep89) (Centrosomal protein 123) (Cep123) (Coiled-coil domain-containing protein 123)
Gene: CEP89

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 783
+	Hs
		900829 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		CEP89_HUMAN (1-783): 8.03e-53: 198: 100.00
+	Hs
		925544 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		CEP89_HUMAN (1-783): 8.03e-53: 198: 100.00
+	Hs
		951255 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		CEP89_HUMAN (1-783): 8.03e-53: 198: 100.00
+	Hs
		900570 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		MRCKA_HUMAN (197-717): 8.92e-48: 186: 17.03
+	Hs
		925344 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		MRCKA_HUMAN (197-717): 8.92e-48: 186: 17.03
+	Hs
		951069 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		MRCKA_HUMAN (197-717): 8.92e-48: 186: 17.03
+	Hs
		724757 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		MYH9_HUMAN (268-774): 1.96e-23: 109: 12.33
+	Hs
		724776 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		MYH9_HUMAN (268-774): 1.96e-23: 109: 12.33
+	Hs
		901094 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		MRCKB_HUMAN (408-744): 1.12e-17: 90.5: 15.30
+	Hs
		925766 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		MRCKB_HUMAN (408-744): 1.12e-17: 90.5: 15.30
+	Hs
		900754 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		MY18A_HUMAN (39-550): 9.2e-17: 87.5: 10.73
+	Hs
		925488 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		MY18A_HUMAN (39-550): 9.2e-17: 87.5: 10.73
+	Hs
		925356 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		MRCKG_HUMAN (200-548): 3.09e-15: 82.4: 14.91
+	Hs
		148608 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		CTRO_HUMAN (73-685): 3.76e-13: 75.8: 12.74
+	Hs
		148653 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		CTRO_HUMAN (73-685): 3.76e-13: 75.8: 12.74
+	Rn
		92842 RHOA_RAT (1-193): 7.11e-82: 242: 92.23		CTRO_RAT (68-671): 2.21e-12: 73.1: 11.92
+	Mm
		823539 RHOA_MOUSE (1-193): 7.11e-82: 242: 92.23		CTRO_MOUSE (97-671): 3.87e-12: 72.4: 11.70
+	Hs
		148297 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		CTRO_HUMAN (73-685): 3.76e-13: 75.8: 12.74
+	Mm
		823530 RAC1_MOUSE (1-193): 7.23e-81: 240: 57.22		CTRO_MOUSE (97-671): 3.87e-12: 72.4: 11.70
+	Hs
		725138 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		MYH10_HUMAN (451-777): 3.75e-11: 69.4: 10.61