HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: IL1AP (Q9NPH3)
Interleukin-1 receptor accessory protein (IL-1 receptor accessory protein) (IL-1RAcP) (EC 3.2.2.6) (Interleukin-1 receptor 3) (IL-1R-3) (IL-1R3)
Gene: IL1RAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 570
+	Hs
		925644 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		IL1AP_HUMAN (1-570): 1.4e-118: 364: 100.00
+	Hs
		915996 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		IL1AP_HUMAN (1-570): 1.4e-118: 364: 100.00
+	Hs
		540389 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		IL1R1_HUMAN (67-566): 2.25e-77: 256: 22.39
+	Hs
		309818 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		I18RA_HUMAN (62-568): 2.5e-65: 225: 23.56
+	Hs
		901110 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		ROBO1_HUMAN (1-281): 7.3e-41: 161: 14.53
+	Hs
		925776 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		ROBO1_HUMAN (1-281): 7.3e-41: 161: 14.53
+	Hs
		436602 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		ROBO1_HUMAN (1-281): 7.3e-41: 161: 14.53
+	Hs
		894644 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		ROBO1_HUMAN (1-281): 7.3e-41: 161: 14.53
+	Hs
		916112 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		ROBO1_HUMAN (1-281): 7.3e-41: 161: 14.53
+	Hs
		915989 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		ROBO2_HUMAN (2-485): 9.28e-38: 151: 11.58
+	Hs
		894276 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		PXDN_HUMAN (138-492): 4.72e-34: 140: 11.14
+	Ce
		136793 RAC1_CAEEL (1-193): 2.88e-81: 241: 53.89		UNC89_CAEEL (1-133): 7.87e-13: 74: 9.70
+	Ce
		104464 G5EBV3_CAEEL (2-193): 4.06e-79: 235: 50.52		UNC89_CAEEL (1-133): 7.87e-13: 74: 9.70
+	Hs
		894044 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		MYLK_HUMAN (24-131): 6.49e-12: 70.9: 16.67
+	Ce
		136794 CDC42_CAEEL (1-193): 1.06e-75: 226: 49.74		UNC89_CAEEL (1-133): 7.87e-13: 74: 9.70
+	Ce
		136800 RHO1_CAEEL (1-192): 1.4e-75: 226: 83.33		UNC89_CAEEL (1-133): 7.87e-13: 74: 9.70