HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: S12A7 (Q9Y666)
Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4)
Gene: SLC12A7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1083
+	Hs
		901099 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		S12A7_HUMAN (1-1083): 0: 1174: 100.00
+	Hs
		925769 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		S12A7_HUMAN (1-1083): 0: 1174: 100.00
+	Hs
		901055 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		S12A4_HUMAN (1-1083): 0: 1105: 69.48
+	Hs
		925735 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		S12A4_HUMAN (1-1083): 0: 1105: 69.48
+	Hs
		436575 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		S12A4_HUMAN (1-1083): 0: 1105: 69.48
+	Hs
		873898 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		S12A2_HUMAN (25-1083): 0: 746: 20.65
+	Hs
		873903 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		S12A2_HUMAN (25-1083): 0: 746: 20.65
+	Hs
		436225 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		S12A2_HUMAN (25-1083): 0: 746: 20.65
+	Hs
		873907 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		S12A2_HUMAN (25-1083): 0: 746: 20.65
+	Hs
		854869 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		CTR2_HUMAN (160-603): 3.52e-94: 316: 16.18
+	Hs
		854874 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		CTR2_HUMAN (160-603): 3.52e-94: 316: 16.18
+	Hs
		436219 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		CTR2_HUMAN (160-603): 3.52e-94: 316: 16.18
+	Hs
		854876 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		CTR2_HUMAN (160-603): 3.52e-94: 316: 16.18
+	Hs
		676530 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		CTR1_HUMAN (160-603): 5.38e-87: 295: 14.35
+	Hs
		676533 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		CTR1_HUMAN (160-603): 5.38e-87: 295: 14.35
+	Hs
		436173 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		CTR1_HUMAN (160-603): 5.38e-87: 295: 14.35
+	Hs
		676536 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		CTR1_HUMAN (160-603): 5.38e-87: 295: 14.35
+	Hs
		900749 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		YLAT2_HUMAN (159-652): 6.01e-78: 267: 12.48
+	Hs
		925480 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		YLAT2_HUMAN (159-652): 6.01e-78: 267: 12.48
+	Hs
		951194 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		YLAT2_HUMAN (159-652): 6.01e-78: 267: 12.48