Interactor 1: 4F2 (P08195)
Amino acid transporter heavy chain SLC3A2 (4F2 cell-surface antigen heavy chain) (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98)
Gene: SLC3A2

Interactor 2: LAT1 (Q01650)
Large neutral amino acids transporter small subunit 1 (4F2 light chain) (4F2 LC) (4F2LC) (CD98 light chain) (Integral membrane protein E16) (E16) (L-type amino acid transporter 1) (hLAT1) (Solute carrier family 7 member 5) (y+ system cationic amino acid transporter)
Gene: SLC7A5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 9829974, 35271311, 30867591, 31160781
Identification Methods affinity chromatography technology, 3D electron microscopy, molecular sieving, comigration in sds page, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, covalent binding, association

The annotation score is based on:

Property Details
Interacting Pfam domains AA_permease_2~Alpha-amylase, AA_permease_2~SLC3A2_N
Common GO terms GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0015828 - tyrosine transport
GO:0009925 - basal plasma membrane
GO:0015829 - valine transport
and 17 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 630
Hs

1 507
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024