Interactor 1: 4F2 (P08195)
Amino acid transporter heavy chain SLC3A2 (4F2 cell-surface antigen heavy chain) (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98)
Gene: SLC3A2

Interactor 2: LAT2 (Q9UHI5)
Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2) (Solute carrier family 7 member 8)
Gene: SLC7A8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.858

The method score is based on:

Property Details
Experiments 32296183, 33961781, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AA_permease_2~Alpha-amylase, AA_permease_2~SLC3A2_N
Common GO terms GO:0005886 - plasma membrane
GO:0006865 - amino acid transport
GO:0009925 - basal plasma membrane
GO:0015829 - valine transport
GO:0015175 - neutral L-amino acid transmembrane transporter activity
and 10 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 630
Hs

1 535
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ Mm
+ Dm

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Last updated: 15 Jul 2024