Interactor 1: 4F2 (P08195)
Amino acid transporter heavy chain SLC3A2 (4F2 cell-surface antigen heavy chain) (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98)
Gene: SLC3A2

Interactor 2: XCT (Q9UPY5)
Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
Gene: SLC7A11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 30709928, 32296183, 34709416, unassigned1304, 34880232
Identification Methods affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, 3D electron microscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AA_permease_2~Alpha-amylase, AA_permease_2~SLC3A2_N
Common GO terms GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0016020 - membrane
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 630
Hs

1 501
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024