HitPredict

Interactor 1: PFKAM (P08237)
ATP-dependent 6-phosphofructokinase, muscle type (ATP-PFK) (PFK-M) (EC 2.7.1.11) (6-phosphofructokinase type A) (Phosphofructo-1-kinase isozyme A) (PFK-A) (Phosphohexokinase)
Gene: PFKM

Interactor 2: PFKAM (P08237)
ATP-dependent 6-phosphofructokinase, muscle type (ATP-PFK) (PFK-M) (EC 2.7.1.11) (6-phosphofructokinase type A) (Phosphofructo-1-kinase isozyme A) (PFK-A) (Phosphohexokinase)
Gene: PFKM

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 25416956, 6444721
Identification Methods two hybrid, two hybrid array, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PFK~PFK
Common GO terms GO:0003872 - 6-phosphofructokinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005945 - 6-phosphofructokinase complex
and 20 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 780
Hs

1 780
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Sc
+ At
+ At
+ At
+ Sa
+ Hs
+ Sp
+ Sc

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Last updated: 15 Jul 2024