HitPredict - High confidence protein-protein interactions

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29930177, 25864199, 32687490
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005524 - ATP binding GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005654 - nucleoplasm and 22 others more... GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006457 - protein folding GO:0006986 - response to unfolded protein GO:0009986 - cell surface GO:0016020 - membrane GO:0016887 - ATP hydrolysis activity GO:0023026 - MHC class II protein complex binding GO:0031072 - heat shock protein binding GO:0031625 - ubiquitin protein ligase binding GO:0034605 - cellular response to heat GO:0034774 - secretory granule lumen GO:0042277 - peptide binding GO:0042470 - melanosome GO:0045296 - cadherin binding GO:0048471 - perinuclear region of cytoplasm GO:0051082 - unfolded protein binding GO:0051726 - regulation of cell cycle GO:0070062 - extracellular exosome GO:0140662 - ATP-dependent protein folding chaperone GO:1904813 - ficolin-1-rich granule lumen
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	724
Hs

1	646

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024