HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: PSA3 (P25788)
Proteasome subunit alpha type-3 (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome component C8)
Gene: PSMA3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30009671, 22079093
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 255
+	Hs
		431551 HS90A_HUMAN (1-724): 0: 1072: 85.25		PSA3_HUMAN (1-255): 5.2e-97: 285: 100.00
+	Hs
		538109 ENPL_HUMAN (3-693): 0: 917: 46.44		PSA3_HUMAN (1-255): 5.2e-97: 285: 100.00
+	Sc
		543379 HSC82_YEAST (13-724): 0: 922: 60.22		PSA5_YEAST (1-255): 3.35e-94: 278: 32.57
+	Sc
		543234 HSC82_YEAST (13-724): 0: 922: 60.22		PSA3_YEAST (8-198): 2.62e-34: 125: 35.42