HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: MATK (P42679)
Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)
Gene: MATK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	22939624
Identification Methods	luminescence based mammalian interactome mapping, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Hs			1 507
+	Hs
		411949 HS90B_HUMAN (1-724): 0: 1086: 100.00		FYN_HUMAN (28-493): 0: 527: 32.23
+	Hs
		433218 HS90B_HUMAN (1-724): 0: 1086: 100.00		YES_HUMAN (4-493): 0: 523: 31.94
+	Hs
		437847 HS90B_HUMAN (1-724): 0: 1086: 100.00		SRC_HUMAN (30-493): 0: 523: 34.52
+	Hs
		437823 HS90B_HUMAN (1-724): 0: 1086: 100.00		FGR_HUMAN (4-494): 0: 519: 32.03
+	Hs
		411556 HS90B_HUMAN (1-724): 0: 1086: 100.00		LCK_HUMAN (39-492): 1.32e-180: 518: 34.62
+	Hs
		411945 HS90A_HUMAN (1-724): 0: 1072: 85.25		FYN_HUMAN (28-493): 0: 527: 32.23
+	Hs
		437817 HS90B_HUMAN (1-724): 0: 1086: 100.00		HCK_HUMAN (26-490): 3.62e-178: 512: 33.47
+	Hs
		431433 HS90A_HUMAN (1-724): 0: 1072: 85.25		YES_HUMAN (4-493): 0: 523: 31.94
+	Hs
		411551 HS90A_HUMAN (1-724): 0: 1072: 85.25		LCK_HUMAN (39-492): 1.32e-180: 518: 34.62
+	Hs
		437967 HS90B_HUMAN (1-724): 0: 1086: 100.00		FRK_HUMAN (22-494): 1.41e-173: 500: 30.91
+	Hs
		337314 HS90B_HUMAN (1-724): 0: 1086: 100.00		ABL1_HUMAN (26-486): 1.44e-165: 499: 32.70
+	Hs
		437960 HS90B_HUMAN (1-724): 0: 1086: 100.00		CSK_HUMAN (45-485): 8.23e-174: 498: 53.05
+	Hs
		437966 HS90B_HUMAN (1-724): 0: 1086: 100.00		ABL2_HUMAN (13-503): 2.01e-164: 498: 31.37
+	Hs
		433526 HS90B_HUMAN (1-724): 0: 1086: 100.00		LYN_HUMAN (14-490): 4.73e-171: 493: 31.73
+	Hs
		438107 HS90B_HUMAN (1-724): 0: 1086: 100.00		ITK_HUMAN (33-484): 4.01e-169: 493: 33.12
+	Hs
		438007 HS90B_HUMAN (1-724): 0: 1086: 100.00		BLK_HUMAN (10-492): 2.69e-169: 489: 32.66
+	Hs
		337312 HS90A_HUMAN (1-724): 0: 1072: 85.25		ABL1_HUMAN (26-486): 1.44e-165: 499: 32.70
+	Hs
		438525 HS90B_HUMAN (1-724): 0: 1086: 100.00		SRMS_HUMAN (1-483): 6.75e-160: 464: 34.34
+	Hs
		437867 HS90B_HUMAN (1-724): 0: 1086: 100.00		FER_HUMAN (75-478): 2.04e-80: 268: 38.86
+	Hs
		438160 HS90B_HUMAN (1-724): 0: 1086: 100.00		PTK6_HUMAN (66-479): 8.11e-80: 258: 38.73