HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: PPARD (Q03181)
Peroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta)
Gene: PPARD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22939624
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 441
+	Hs
		431759 HS90A_HUMAN (1-724): 0: 1072: 85.25		PPARD_HUMAN (1-441): 5.15e-125: 371: 100.00
+	Hs
		437955 HS90B_HUMAN (1-724): 0: 1086: 100.00		PPARG_HUMAN (13-441): 3.64e-114: 346: 57.28
+	Hs
		431608 HS90A_HUMAN (1-724): 0: 1072: 85.25		PPARG_HUMAN (13-441): 3.64e-114: 346: 57.28
+	Hs
		431775 HS90A_HUMAN (1-724): 0: 1072: 85.25		PPARA_HUMAN (15-441): 4.62e-112: 339: 64.72
+	Hs
		368839 HS90B_HUMAN (1-724): 0: 1086: 100.00		ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82
+	Hs
		438124 HS90B_HUMAN (1-724): 0: 1086: 100.00		NR1H3_HUMAN (4-437): 4.61e-103: 315: 25.00
+	Hs
		437840 HS90B_HUMAN (1-724): 0: 1086: 100.00		VDR_HUMAN (57-439): 7.97e-102: 311: 24.16
+	Hs
		320158 HS90B_HUMAN (1-724): 0: 1086: 100.00		ERR2_HUMAN (2-438): 1.58e-99: 305: 19.64
+	Hs
		368832 HS90A_HUMAN (1-724): 0: 1072: 85.25		ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82
+	Hs
		431801 HS90A_HUMAN (1-724): 0: 1072: 85.25		NR1H3_HUMAN (4-437): 4.61e-103: 315: 25.00
+	Hs
		320155 HS90A_HUMAN (1-724): 0: 1072: 85.25		ERR2_HUMAN (2-438): 1.58e-99: 305: 19.64
+	Hs
		368916 ENPL_HUMAN (3-693): 0: 917: 46.44		ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82
+	Hs
		538114 ENPL_HUMAN (3-693): 0: 917: 46.44		RXRB_HUMAN (29-438): 1.2e-100: 312: 25.00
+	Hs
		437901 HS90B_HUMAN (1-724): 0: 1086: 100.00		NR4A1_HUMAN (38-439): 6.71e-30: 124: 29.26
+	Hs
		265846 HS90B_HUMAN (1-724): 0: 1086: 100.00		NR1I2_HUMAN (74-437): 2.75e-30: 123: 25.98
+	Hs
		265845 HS90A_HUMAN (1-724): 0: 1072: 85.25		NR1I2_HUMAN (74-437): 2.75e-30: 123: 25.98
+	Hs
		538103 ENPL_HUMAN (3-693): 0: 917: 46.44		NR4A1_HUMAN (38-439): 6.71e-30: 124: 29.26