Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: PDK2 (Q15119)
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII)
Gene: PDK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 32707033
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c~HSP90
Common GO terms GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0042803 - protein homodimerization activity
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 724
Hs

1 407
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024