HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: TNI3K (Q59H18)
Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)
Gene: TNNI3K

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Hs			1 835
+	Hs
		431933 HS90A_HUMAN (1-724): 0: 1072: 85.25		TNI3K_HUMAN (1-835): 0: 712: 100.00
+	Hs
		438029 HS90B_HUMAN (1-724): 0: 1086: 100.00		EPHA4_HUMAN (335-832): 7.7e-112: 366: 19.96
+	Hs
		438028 HS90B_HUMAN (1-724): 0: 1086: 100.00		EPHB1_HUMAN (339-830): 1.64e-111: 365: 21.87
+	Hs
		411556 HS90B_HUMAN (1-724): 0: 1086: 100.00		LCK_HUMAN (243-734): 5.71e-113: 355: 17.75
+	Hs
		431692 HS90A_HUMAN (1-724): 0: 1072: 85.25		EPHA4_HUMAN (335-832): 7.7e-112: 366: 19.96
+	Hs
		431691 HS90A_HUMAN (1-724): 0: 1072: 85.25		EPHB1_HUMAN (339-830): 1.64e-111: 365: 21.87
+	Hs
		411551 HS90A_HUMAN (1-724): 0: 1072: 85.25		LCK_HUMAN (243-734): 5.71e-113: 355: 17.75
+	Hs
		108852 HS90B_HUMAN (1-724): 0: 1086: 100.00		H0YE48_HUMAN (477-642): 2.03e-101: 313: 80.85
+	Hs
		438082 HS90B_HUMAN (1-724): 0: 1086: 100.00		ANK2_HUMAN (4-254): 4.7e-62: 231: 25.50
+	Hs
		438088 HS90B_HUMAN (1-724): 0: 1086: 100.00		M3K10_HUMAN (462-720): 1.28e-39: 160: 35.42
+	Hs
		201182 HS90B_HUMAN (1-724): 0: 1086: 100.00		M3K7_HUMAN (462-716): 9.43e-40: 157: 37.55
+	Hs
		431754 HS90A_HUMAN (1-724): 0: 1072: 85.25		M3K10_HUMAN (462-720): 1.28e-39: 160: 35.42
+	Hs
		201181 HS90A_HUMAN (1-724): 0: 1072: 85.25		M3K7_HUMAN (462-716): 9.43e-40: 157: 37.55
+	Mm
		432432 HS90A_MOUSE (1-724): 0: 1068: 84.31		M3K7_MOUSE (462-716): 7.84e-40: 157: 37.55
+	Hs
		438117 HS90B_HUMAN (1-724): 0: 1086: 100.00		ANK3_HUMAN (206-525): 7.51e-31: 133: 19.12
+	Zm
		8229 A0A1D6LMW9_MAIZE (5-693): 0: 852: 46.66		A0A1D6ELX5_MAIZE (458-727): 1.36e-102: 336: 34.19
+	Hs
		438135 HS90B_HUMAN (1-724): 0: 1086: 100.00		ILK_HUMAN (18-159): 2.4e-17: 87.7: 15.49
+	Hs
		431816 HS90A_HUMAN (1-724): 0: 1072: 85.25		ILK_HUMAN (18-159): 2.4e-17: 87.7: 15.49
+	Mm
		223271 HS90A_MOUSE (1-724): 0: 1068: 84.31		ILK_MOUSE (18-159): 2.58e-17: 87.3: 15.49
+	Hs
		201198 ENPL_HUMAN (3-693): 0: 917: 46.44		M3K7_HUMAN (462-716): 9.43e-40: 157: 37.55