Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: CD37L (Q7L3B6)
Hsp90 co-chaperone Cdc37-like 1 (Hsp90-associating relative of Cdc37)
Gene: CDC37L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.911

The method score is based on:

Property Details
Experiments 25416956, 33961781, 21988832, 25036637
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC37_M~HSP90
Common GO terms GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006457 - protein folding
GO:0031072 - heat shock protein binding
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 724
Hs

1 337
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Dm
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024