HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: UN45B (Q8IWX7)
Protein unc-45 homolog B (Unc-45B) (SMUNC45)
Gene: UNC45B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Hs			1 931
+	Hs
		111940 K9JA46_HUMAN (1-724): 0: 1072: 85.25		UN45B_HUMAN (1-931): 0: 998: 100.00
+	Hs
		438524 HS90B_HUMAN (1-724): 0: 1086: 100.00		UN45A_HUMAN (6-929): 0: 924: 56.65
+	Hs
		438533 HS90B_HUMAN (1-724): 0: 1086: 100.00		RPAP3_HUMAN (1-327): 6e-46: 178: 16.12
+	Hs
		297025 HS90B_HUMAN (1-724): 0: 1086: 100.00		TOM70_HUMAN (2-387): 1.32e-40: 161: 15.82
+	Hs
		438590 HS90B_HUMAN (1-724): 0: 1086: 100.00		Z3H7B_HUMAN (3-162): 2.21e-39: 160: 26.86
+	Mm
		513680 HS90B_MOUSE (1-724): 0: 1089: 99.59		PPP5_MOUSE (4-155): 1e-36: 147: 27.45
+	Hs
		297024 HS90A_HUMAN (1-724): 0: 1072: 85.25		TOM70_HUMAN (2-387): 1.32e-40: 161: 15.82
+	Hs
		438021 HS90B_HUMAN (1-724): 0: 1086: 100.00		PPP5_HUMAN (2-155): 1.26e-36: 147: 28.39
+	Mm
		513709 HS90B_MOUSE (1-724): 0: 1089: 99.59		CHIP_MOUSE (6-146): 9.32e-37: 142: 27.66
+	Hs
		213454 HS90B_HUMAN (1-724): 0: 1086: 100.00		SGTA_HUMAN (4-126): 6.85e-37: 143: 30.89
+	Hs
		438621 HS90B_HUMAN (1-724): 0: 1086: 100.00		CHIP_HUMAN (6-146): 9.82e-37: 142: 27.66
+	Hs
		111935 K9JA46_HUMAN (1-724): 0: 1072: 85.25		PPP5_HUMAN (2-155): 1.26e-36: 147: 28.39
+	Hs
		213451 HS90A_HUMAN (1-724): 0: 1072: 85.25		SGTA_HUMAN (4-126): 6.85e-37: 143: 30.89
+	Hs
		174561 HS90B_HUMAN (1-724): 0: 1086: 100.00		OGT1_HUMAN (6-407): 2.59e-28: 124: 12.90
+	Hs
		437930 HS90B_HUMAN (1-724): 0: 1086: 100.00		STIP1_HUMAN (4-427): 5.12e-27: 118: 12.82
+	Hs
		174556 HS90A_HUMAN (1-724): 0: 1072: 85.25		OGT1_HUMAN (6-407): 2.59e-28: 124: 12.90
+	Hs
		438201 HS90B_HUMAN (1-724): 0: 1086: 100.00		TOM34_HUMAN (7-131): 9.33e-25: 107: 26.92
+	Hs
		111934 K9JA46_HUMAN (1-724): 0: 1072: 85.25		STIP1_HUMAN (4-427): 5.12e-27: 118: 12.82
+	Hs
		431574 HS90A_HUMAN (1-724): 0: 1072: 85.25		STIP1_HUMAN (4-427): 5.12e-27: 118: 12.82
+	Hs
		438106 HS90B_HUMAN (1-724): 0: 1086: 100.00		PPID_HUMAN (9-142): 2.04e-09: 62.4: 28.38