HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: FXL14 (Q8N1E6)
F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14)
Gene: FBXL14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22939624
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 418
+	Hs
		432050 HS90A_HUMAN (1-724): 0: 1072: 85.25		FXL14_HUMAN (1-418): 3.24e-73: 236: 100.00
+	Hs
		438527 HS90B_HUMAN (1-724): 0: 1086: 100.00		FXL15_HUMAN (114-379): 2.98e-31: 122: 24.44
+	Hs
		431842 HS90A_HUMAN (1-724): 0: 1072: 85.25		SCRIB_HUMAN (132-417): 5.28e-30: 125: 12.95
+	Hs
		432261 HS90A_HUMAN (1-724): 0: 1072: 85.25		FXL15_HUMAN (114-379): 2.98e-31: 122: 24.44
+	Hs
		438605 HS90B_HUMAN (1-724): 0: 1086: 100.00		FBXL4_HUMAN (180-391): 3.38e-20: 94.7: 25.89
+	Hs
		438607 HS90B_HUMAN (1-724): 0: 1086: 100.00		FBXL2_HUMAN (255-416): 1.88e-20: 94.6: 25.90
+	Hs
		432347 HS90A_HUMAN (1-724): 0: 1072: 85.25		FBXL4_HUMAN (180-391): 3.38e-20: 94.7: 25.89
+	Hs
		432349 HS90A_HUMAN (1-724): 0: 1072: 85.25		FBXL2_HUMAN (255-416): 1.88e-20: 94.6: 25.90
+	Hs
		438362 HS90B_HUMAN (1-724): 0: 1086: 100.00		FXL13_HUMAN (155-417): 6.31e-14: 75.7: 15.94
+	Hs
		432071 HS90A_HUMAN (1-724): 0: 1072: 85.25		FXL13_HUMAN (155-417): 6.31e-14: 75.7: 15.94
+	Hs
		1162511 Q6PK50_HUMAN (1-350): 0: 618: 99.71		FXL14_HUMAN (1-418): 3.24e-73: 236: 100.00
+	Hs
		72080 Q6PK50_HUMAN (1-350): 0: 618: 99.71		B3KM70_HUMAN (255-416): 3.88e-20: 93.8: 25.90