HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: TRIM2 (Q9C040)
Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING finger protein 86) (RING-type E3 ubiquitin transferase TRIM2)
Gene: TRIM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22939624
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Hs			1 744
+	Hs
		432239 HS90A_HUMAN (1-724): 0: 1072: 85.25		TRIM2_HUMAN (1-744): 0: 649: 100.00
+	Hs
		438479 HS90B_HUMAN (1-724): 0: 1086: 100.00		TRI56_HUMAN (1-742): 3.7e-97: 319: 19.63
+	Hs
		437880 HS90B_HUMAN (1-724): 0: 1086: 100.00		RO52_HUMAN (8-498): 1.12e-95: 306: 16.17
+	Hs
		432214 HS90A_HUMAN (1-724): 0: 1072: 85.25		TRI56_HUMAN (1-742): 3.7e-97: 319: 19.63
+	Hs
		438120 HS90B_HUMAN (1-724): 0: 1086: 100.00		TRI32_HUMAN (1-742): 1.44e-89: 296: 18.33
+	Hs
		431794 HS90A_HUMAN (1-724): 0: 1072: 85.25		TRI32_HUMAN (1-742): 1.44e-89: 296: 18.33
+	Hs
		438502 HS90B_HUMAN (1-724): 0: 1086: 100.00		TRIM6_HUMAN (10-490): 4.9e-81: 268: 13.75
+	Hs
		438501 HS90B_HUMAN (1-724): 0: 1086: 100.00		TRIM7_HUMAN (4-467): 5.15e-76: 256: 17.20
+	Hs
		438654 HS90B_HUMAN (1-724): 0: 1086: 100.00		TRI17_HUMAN (8-490): 3.27e-74: 250: 13.12
+	Hs
		438587 HS90B_HUMAN (1-724): 0: 1086: 100.00		TRI10_HUMAN (8-484): 1.33e-72: 246: 14.68
+	Hs
		432238 HS90A_HUMAN (1-724): 0: 1072: 85.25		TRIM7_HUMAN (4-467): 5.15e-76: 256: 17.20
+	Hs
		432399 HS90A_HUMAN (1-724): 0: 1072: 85.25		TRI17_HUMAN (8-490): 3.27e-74: 250: 13.12
+	Hs
		432329 HS90A_HUMAN (1-724): 0: 1072: 85.25		TRI10_HUMAN (8-484): 1.33e-72: 246: 14.68
+	Hs
		175632 HS90A_HUMAN (1-724): 0: 1072: 85.25		TRI18_HUMAN (15-449): 2.83e-65: 230: 16.51
+	Hs
		538271 ENPL_HUMAN (3-693): 0: 917: 46.44		TRI68_HUMAN (8-491): 5.51e-89: 289: 13.36
+	Hs
		62676 ENPL_HUMAN (3-693): 0: 917: 46.44		TRI64_HUMAN (11-477): 6.92e-76: 253: 15.55
+	Hs
		438286 HS90B_HUMAN (1-724): 0: 1086: 100.00		NHLC1_HUMAN (1-113): 3.39e-13: 74.2: 18.03
+	Hs
		431597 HS90A_HUMAN (1-724): 0: 1072: 85.25		TRI23_HUMAN (19-172): 3.16e-15: 81.3: 30.72
+	Hs
		170238 ENPL_HUMAN (3-693): 0: 917: 46.44		TIF1A_HUMAN (22-327): 7.48e-64: 232: 18.25
+	Hs
		431976 HS90A_HUMAN (1-724): 0: 1072: 85.25		NHLC1_HUMAN (1-113): 3.39e-13: 74.2: 18.03