HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: Q9H4D1 (Q9H4D1)
Protein kinase
Gene: dik

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29435596
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP90~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 784
+	Hs
		432263 HS90A_HUMAN (1-724): 0: 1072: 85.25		Q9H4D1_HUMAN (1-784): 0: 712: 100.00
+	Hs
		432186 HS90A_HUMAN (1-724): 0: 1072: 85.25		Q96T11_HUMAN (1-784): 0: 705: 99.49
+	Hs
		431704 HS90A_HUMAN (1-724): 0: 1072: 85.25		RIPK4_HUMAN (1-784): 0: 693: 93.99
+	Hs
		538399 ENPL_HUMAN (3-693): 0: 917: 46.44		Q9H4D1_HUMAN (1-784): 0: 712: 100.00
+	Hs
		538174 ENPL_HUMAN (3-693): 0: 917: 46.44		RIPK4_HUMAN (1-784): 0: 693: 93.99
+	Hs
		431682 HS90A_HUMAN (1-724): 0: 1072: 85.25		DAPK1_HUMAN (464-783): 4.07e-81: 286: 25.39
+	Hs
		438082 HS90B_HUMAN (1-724): 0: 1086: 100.00		ANK2_HUMAN (328-623): 7.99e-64: 235: 23.57
+	Hs
		201744 HS90A_HUMAN (1-724): 0: 1072: 85.25		RIPK2_HUMAN (31-284): 2.18e-54: 198: 44.36
+	Hs
		438117 HS90B_HUMAN (1-724): 0: 1086: 100.00		ANK3_HUMAN (611-784): 2.5e-46: 182: 32.57
+	Hs
		438365 HS90B_HUMAN (1-724): 0: 1086: 100.00		ANKK1_HUMAN (333-607): 8.82e-45: 174: 22.10
+	Hs
		432073 HS90A_HUMAN (1-724): 0: 1072: 85.25		ANKK1_HUMAN (333-607): 8.82e-45: 174: 22.10
+	Hs
		438651 HS90B_HUMAN (1-724): 0: 1086: 100.00		RIPK3_HUMAN (21-286): 1.6e-35: 143: 35.74
+	Hs
		432396 HS90A_HUMAN (1-724): 0: 1072: 85.25		RIPK3_HUMAN (21-286): 1.6e-35: 143: 35.74
+	Hs
		1123425 H90B4_HUMAN (25-596): 0: 639: 71.85		ANKK1_HUMAN (333-607): 8.82e-45: 174: 22.10