HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: FXL12 (Q9NXK8)
F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12)
Gene: FBXL12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22939624
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 326
+	Hs
		432307 HS90A_HUMAN (1-724): 0: 1072: 85.25		FXL12_HUMAN (1-326): 6.61e-68: 217: 100.00
+	Hs
		438132 HS90B_HUMAN (1-724): 0: 1086: 100.00		SKP2_HUMAN (3-263): 1.26e-37: 140: 21.13
+	Hs
		431812 HS90A_HUMAN (1-724): 0: 1072: 85.25		SKP2_HUMAN (3-263): 1.26e-37: 140: 21.13
+	Hs
		438345 HS90B_HUMAN (1-724): 0: 1086: 100.00		FXL14_HUMAN (121-326): 1.17e-20: 93.5: 21.66
+	Hs
		438605 HS90B_HUMAN (1-724): 0: 1086: 100.00		FBXL4_HUMAN (41-229): 2.29e-20: 93.5: 16.24
+	Hs
		432050 HS90A_HUMAN (1-724): 0: 1072: 85.25		FXL14_HUMAN (121-326): 1.17e-20: 93.5: 21.66
+	Hs
		432347 HS90A_HUMAN (1-724): 0: 1072: 85.25		FBXL4_HUMAN (41-229): 2.29e-20: 93.5: 16.24
+	Hs
		438607 HS90B_HUMAN (1-724): 0: 1086: 100.00		FBXL2_HUMAN (5-206): 1.49e-15: 78.9: 16.35
+	Hs
		438362 HS90B_HUMAN (1-724): 0: 1086: 100.00		FXL13_HUMAN (18-203): 3.08e-12: 69.3: 11.68
+	Hs
		432349 HS90A_HUMAN (1-724): 0: 1072: 85.25		FBXL2_HUMAN (5-206): 1.49e-15: 78.9: 16.35
+	Hs
		438527 HS90B_HUMAN (1-724): 0: 1086: 100.00		FXL15_HUMAN (6-230): 3.79e-11: 64.7: 22.44
+	Hs
		432071 HS90A_HUMAN (1-724): 0: 1072: 85.25		FXL13_HUMAN (18-203): 3.08e-12: 69.3: 11.68
+	Hs
		432261 HS90A_HUMAN (1-724): 0: 1072: 85.25		FXL15_HUMAN (6-230): 3.79e-11: 64.7: 22.44
+	Hs
		1162511 Q6PK50_HUMAN (1-350): 0: 618: 99.71		FXL14_HUMAN (121-326): 1.17e-20: 93.5: 21.66
+	Hs
		72080 Q6PK50_HUMAN (1-350): 0: 618: 99.71		B3KM70_HUMAN (5-206): 9.54e-16: 79.3: 16.35