Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: KCC2A (Q9UQM7)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)
Gene: CAMK2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.817

The method score is based on:

Property Details
Experiments 31980649, unassigned2173, 22939624
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HSP90~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 724
Hs

1 478
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Last updated: 15 Jul 2024