HitPredict

Interactor 1: SRPRA (P08240)
Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha)
Gene: SRPRA

Interactor 2: ROS1 (P08922)
Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)
Gene: ROS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 638 Hs			1 2347
+	Hs
		438699 SRPRA_HUMAN (1-638): 0: 783: 100.00		EPHA8_HUMAN (1383-2242): 1.9e-173: 562: 18.61
+	Hs
		411277 SRPRA_HUMAN (1-638): 0: 783: 100.00		INSR_HUMAN (1424-2308): 7.33e-167: 555: 23.13
+	Hs
		435498 SRPRA_HUMAN (1-638): 0: 783: 100.00		IGF1R_HUMAN (1442-2307): 3.63e-161: 538: 23.25
+	Hs
		438676 SRPRA_HUMAN (1-638): 0: 783: 100.00		INSRR_HUMAN (1472-2261): 4.5e-161: 536: 24.97
+	Hs
		438749 SRPRA_HUMAN (1-638): 0: 783: 100.00		TYRO3_HUMAN (1514-2218): 1.53e-145: 479: 23.85
+	Hs
		438702 SRPRA_HUMAN (1-638): 0: 783: 100.00		UFO_HUMAN (1633-2297): 6.04e-130: 434: 25.83
+	Hs
		438889 SRPRA_HUMAN (1-638): 0: 783: 100.00		ALK_HUMAN (1858-2311): 4.31e-84: 309: 38.96
+	Hs
		434117 SRPRA_HUMAN (1-638): 0: 783: 100.00		RET_HUMAN (1940-2216): 6.4e-64: 241: 42.76
+	Hs
		438692 SRPRA_HUMAN (1-638): 0: 783: 100.00		FGFR3_HUMAN (1886-2215): 4.22e-59: 222: 38.73