Interactor 1: ELNE (P08246)
Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human leukocyte elastase) (HLE) (Medullasin) (PMN elastase)
Gene: ELANE

Interactor 2: MMP9 (P14780)
Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]
Gene: MMP9

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 0.60 0.457

The method score is based on:

Property Details
Experiments 19506020
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004175 - endopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006508 - proteolysis
and 4 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 267
Hs

1 707
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024