HitPredict

Interactor 1: MMP2 (P08253)
72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX]
Gene: MMP2

Interactor 2: CO4A2 (P08572)
Collagen alpha-2(IV) chain [Cleaved into: Canstatin]
Gene: COL4A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.628

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001525 - angiogenesis
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0014823 - response to activity
GO:0030198 - extracellular matrix organization
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 660
Hs

1 1712
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Last updated: 15 Jul 2024