HitPredict

Interactor 1: MMP2 (P08253)
72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX]
Gene: MMP2

Interactor 2: COEA1 (Q05707)
Collagen alpha-1(XIV) chain (Undulin)
Gene: COL14A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0030198 - extracellular matrix organization GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 660 Hs			1 1796
+	Hs
		540424 MMP9_HUMAN (21-660): 0: 711: 44.40		COEA1_HUMAN (1-1796): 0: 1030: 97.02
+	Hs
		439253 MMP2_HUMAN (1-660): 0: 912: 100.00		COCA1_HUMAN (11-534): 7.8e-29: 129: 16.60
+	Hs
		439222 MMP2_HUMAN (1-660): 0: 912: 100.00		CO6A2_HUMAN (1462-1705): 1.64e-20: 101: 36.43
+	Hs
		362710 MMP2_HUMAN (1-660): 0: 912: 100.00		FINC_HUMAN (17-516): 3.82e-17: 90.4: 14.57
+	Hs
		358647 MMP2_HUMAN (1-660): 0: 912: 100.00		CO4A1_HUMAN (1462-1755): 4.59e-13: 77: 35.71
+	Hs
		439220 MMP2_HUMAN (1-660): 0: 912: 100.00		CO4A2_HUMAN (1437-1679): 1.54e-11: 72: 28.99
+	Hs
		540439 MMP9_HUMAN (21-660): 0: 711: 44.40		COCA1_HUMAN (11-534): 7.8e-29: 129: 16.60
+	Hs
		517985 MMP9_HUMAN (21-660): 0: 711: 44.40		CO6A2_HUMAN (1462-1705): 1.64e-20: 101: 36.43
+	Hs
		362773 MMP9_HUMAN (21-660): 0: 711: 44.40		FINC_HUMAN (17-516): 3.82e-17: 90.4: 14.57
+	Hs
		358650 MMP9_HUMAN (21-660): 0: 711: 44.40		CO4A1_HUMAN (1462-1755): 4.59e-13: 77: 35.71
+	Hs
		441053 MMP9_HUMAN (21-660): 0: 711: 44.40		CO4A2_HUMAN (1437-1679): 1.54e-11: 72: 28.99
+	Hs
		439270 MMP3_HUMAN (18-229): 4.24e-90: 290: 44.95		PTPRS_HUMAN (3-1060): 5.36e-85: 312: 12.37
+	Hs
		362808 FINC_HUMAN (255-405): 8.74e-31: 131: 42.24		CO9A1_HUMAN (1384-1774): 3.42e-51: 199: 26.94
+	Hs
		363093 FINC_HUMAN (255-405): 8.74e-31: 131: 42.24		CO7A1_HUMAN (20-916): 7.42e-47: 188: 18.31
+	Hs
		362655 FINC_HUMAN (255-405): 8.74e-31: 131: 42.24		FINC_HUMAN (17-516): 3.82e-17: 90.4: 14.57
+	Hs
		362826 FINC_HUMAN (255-405): 8.74e-31: 131: 42.24		TENA_HUMAN (19-141): 4.04e-11: 70.8: 17.89
+	Hs
		363240 FINC_HUMAN (255-405): 8.74e-31: 131: 42.24		TITIN_HUMAN (46-216): 4.26e-10: 67.7: 13.48