Interactor 1: MMP2 (P08253)
72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX]
Gene: MMP2
Interactor 2: PCSK9 (Q8NBP7)
Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-) (Neural apoptosis-regulated convertase 1) (NARC-1) (Proprotein convertase 9) (PC9) (Subtilisin/kexin-like protease PC9)
Gene: PCSK9
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 0.60 | 0.586 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25613181 |
| Identification Methods | enzymatic study, zymography, blue native page |
| Interaction Type | cleavage reaction, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0004252 - serine-type endopeptidase activity GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005886 - plasma membrane |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
