HitPredict

Interactor 1: CATG (P08311)
Cathepsin G (CG) (EC 3.4.21.20) [Cleaved into: Cathepsin G, C-terminal truncated form]
Gene: CTSG

Interactor 2: SPB4 (P48594)
Serpin B4 (Leupin) (Peptidase inhibitor 11) (PI-11) (Squamous cell carcinoma antigen 2) (SCCA-2)
Gene: SERPINB4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12949073
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Serpin~Trypsin
Common GO terms	GO:0005615 - extracellular space GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 255 Hs			1 390
+	Hs
		428671 TRY1_HUMAN (1-246): 9.61e-118: 338: 35.18		SPB8_HUMAN (1-390): 4.5e-152: 435: 44.64
+	Hs
		486155 GRAB_HUMAN (1-245): 1.64e-99: 292: 56.68		SPB9_HUMAN (1-390): 9.15e-166: 470: 45.15
+	Hs
		714770 TRY3_HUMAN (8-246): 3.04e-111: 323: 32.92		SPB12_HUMAN (1-390): 5.43e-146: 421: 47.29
+	Hs
		719387 KLK13_HUMAN (1-252): 2.09e-101: 298: 33.33		SPB6_HUMAN (1-390): 3e-156: 446: 45.27
+	Mm
		1141519 KLK8_MOUSE (1-246): 4.32e-97: 286: 32.95		SPB6_MOUSE (1-390): 1.47e-158: 452: 45.39
+	Hs
		589593 KLK2_HUMAN (1-245): 2.59e-97: 287: 30.57		SPB6_HUMAN (1-390): 3e-156: 446: 45.27
+	Mm
		430527 Q9Z1R9_MOUSE (1-245): 1.1e-116: 335: 34.13		A1AT1_MOUSE (4-390): 3.2e-135: 394: 31.88
+	Hs
		371463 KLKB1_HUMAN (10-254): 5.6e-102: 311: 27.13		IPSP_HUMAN (10-390): 6.43e-137: 398: 31.15
+	Hs
		344349 KLK13_HUMAN (1-252): 2.09e-101: 298: 33.33		AACT_HUMAN (4-390): 8.94e-140: 406: 33.08
+	Hs
		344097 KLK1_HUMAN (1-246): 2.45e-97: 287: 32.21		ANT3_HUMAN (4-390): 4.25e-142: 413: 38.42
+	Hs
		344266 CATG_HUMAN (1-255): 1.05e-98: 290: 100.00		AACT_HUMAN (4-390): 8.94e-140: 406: 33.08
+	Hs
		371455 FA11_HUMAN (13-244): 6.14e-97: 297: 28.57		IPSP_HUMAN (10-390): 6.43e-137: 398: 31.15
+	Hs
		344274 KLK2_HUMAN (1-245): 2.59e-97: 287: 30.57		AACT_HUMAN (4-390): 8.94e-140: 406: 33.08
+	Hs
		344148 KLK1_HUMAN (1-246): 2.45e-97: 287: 32.21		A1AT_HUMAN (2-390): 3.71e-139: 404: 32.82
+	Hs
		344172 CTRL_HUMAN (10-245): 3.03e-95: 281: 32.11		A1AT_HUMAN (2-390): 3.71e-139: 404: 32.82
+	Hs
		397636 KLK2_HUMAN (1-245): 2.59e-97: 287: 30.57		IPSP_HUMAN (10-390): 6.43e-137: 398: 31.15
+	Hs
		341339 PLMN_HUMAN (19-245): 2.18e-96: 301: 32.50		PAI1_HUMAN (9-390): 3.44e-126: 371: 30.16
+	Hs
		621770 PRTN3_HUMAN (20-243): 1.73e-41: 144: 37.50		ILEU_HUMAN (1-390): 1.86e-151: 434: 46.72
+	Hs
		344100 GRAA_HUMAN (20-243): 5.91e-43: 148: 38.24		ANT3_HUMAN (4-390): 4.25e-142: 413: 38.42
+	Hs
		344162 PRTN3_HUMAN (20-243): 1.73e-41: 144: 37.50		A1AT_HUMAN (2-390): 3.71e-139: 404: 32.82