HitPredict

Interactor 1: CATG (P08311)
Cathepsin G (CG) (EC 3.4.21.20) [Cleaved into: Cathepsin G, C-terminal truncated form]
Gene: CTSG

Interactor 2: ISK5 (Q9NQ38)
Serine protease inhibitor Kazal-type 5 (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Cleaved into: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665]
Gene: SPINK5

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22588119
Identification Methods	protein array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Kazal_1~Trypsin
Common GO terms	GO:0005576 - extracellular region GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1064
+	Hs
		1343117 KLK13_HUMAN (1-252): 2.09e-101: 298: 33.33		ISK5_HUMAN (1-1064): 9.18e-146: 465: 100.00
+	Hs
		1343116 KLK14_HUMAN (1-244): 5.56e-99: 291: 35.34		ISK5_HUMAN (1-1064): 9.18e-146: 465: 100.00
+	Hs
		836334 KLK7_HUMAN (16-246): 2.86e-35: 128: 35.59		ISK5_HUMAN (1-1064): 9.18e-146: 465: 100.00
+	Hs
		129648 TRY1_HUMAN (1-246): 9.61e-118: 338: 35.18		AGRIN_HUMAN (299-1063): 9.35e-18: 91.7: 11.62
+	Hs
		1204963 KLK11_HUMAN (18-245): 3.22e-98: 290: 32.07		FRAS1_HUMAN (28-712): 3.17e-24: 112: 9.85
+	Hs
		439344 CATG_HUMAN (1-255): 1.05e-98: 290: 100.00		FRAS1_HUMAN (28-712): 3.17e-24: 112: 9.85
+	Hs
		621376 CMA1_HUMAN (13-245): 3.64e-96: 283: 50.64		FRAS1_HUMAN (28-712): 3.17e-24: 112: 9.85
+	Hs
		439352 CATG_HUMAN (1-255): 1.05e-98: 290: 100.00		SORL_HUMAN (29-592): 2.64e-16: 86.7: 8.48
+	Hs
		621380 CMA1_HUMAN (13-245): 3.64e-96: 283: 50.64		SORL_HUMAN (29-592): 2.64e-16: 86.7: 8.48
+	Hs
		341357 PLMN_HUMAN (19-245): 2.18e-96: 301: 32.50		LAMA1_HUMAN (686-891): 8.51e-09: 62: 11.37
+	Hs
		172637 GRAB_HUMAN (1-245): 1.64e-99: 292: 56.68		LAMA5_HUMAN (73-380): 5.12e-10: 66.2: 8.20
+	Hs
		621801 PRTN3_HUMAN (20-243): 1.73e-41: 144: 37.50		FRAS1_HUMAN (28-712): 3.17e-24: 112: 9.85
+	Mm
		112094 CFAD_MOUSE (5-238): 1.99e-36: 131: 32.93		M0QWP1_MOUSE (408-1050): 2.45e-17: 90.1: 14.45
+	Mm
		358681 CFAD_MOUSE (5-238): 1.99e-36: 131: 32.93		LAMB1_MOUSE (61-424): 2.59e-09: 63.9: 8.68
+	Mm
		371919 CFAD_MOUSE (5-238): 1.99e-36: 131: 32.93		LAMA5_MOUSE (744-983): 6.16e-09: 62.8: 7.23