Interactor 1: IL6 (P08505)
Interleukin-6 (IL-6) (B-cell hybridoma growth factor) (Interleukin HP-1)
Gene: IL6

Interactor 2: NFKB1 (P25799)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (NF-kappa-B1 p84/NF-kappa-B1 p98) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 15241416, 17982049, 19782405
Identification Methods anti tag coimmunoprecipitation, electrophoretic mobility supershift assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0010467 - gene expression
GO:0010628 - positive regulation of gene expression
GO:0045893 - positive regulation of DNA-templated transcription
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0071222 - cellular response to lipopolysaccharide
and 4 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 211
Mm

1 971
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm

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Last updated: 15 Jul 2024