Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: BDNF (P23560)
Neurotrophic factor BDNF precursor form (proBDNF) (Abrineurin) (Brain-derived neurotrophic factor) [Cleaved into: Neurotrophic factor BDNF]
Gene: BDNF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 0.55 0.493

The method score is based on:

Property Details
Experiments 32814053
Identification Methods two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0007411 - axon guidance
GO:0010976 - positive regulation of neuron projection development
GO:0030425 - dendrite
GO:0043524 - negative regulation of neuron apoptotic process
and 2 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 11Aug2025