Interactor 1: CD14 (P08571)
Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein) (CD antigen CD14) [Cleaved into: Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane-bound form]
Gene: CD14

Interactor 2: TLR8 (Q9NR97)
Toll-like receptor 8 (CD antigen CD288)
Gene: TLR8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21078886
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_6~LRR_8
Common GO terms GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0009897 - external side of plasma membrane
GO:0010008 - endosome membrane
GO:0032729 - positive regulation of type II interferon production
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 375
Hs

1 1041
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024