Interactor 1: PTPRC (P08575)
Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45)
Gene: PTPRC

Interactor 2: PTPRC (P08575)
Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45)
Gene: PTPRC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 10683443, 15978577
Identification Methods two hybrid, comigration in sds page, tox-r dimerization assay
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~fn3, Y_phosphatase~Y_phosphatase
Common GO terms GO:0000165 - MAPK cascade
GO:0001779 - natural killer cell differentiation
GO:0001915 - negative regulation of T cell mediated cytotoxicity
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0001960 - negative regulation of cytokine-mediated signaling pathway
and 79 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1306
Hs

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Last updated: 15 Jul 2024