Interactor 1: PTPRC (P08575)
Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45)
Gene: PTPRC

Interactor 2: SEM4D (Q92854)
Semaphorin-4D (A8) (BB18) (GR3) (CD antigen CD100)
Gene: SEMA4D

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 8955171, 10648410
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~ig
Common GO terms GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0050731 - positive regulation of peptidyl-tyrosine phosphorylation
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1306
Hs

1 862
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024