HitPredict

Interactor 1: RU2B (P08579)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: SNRPB2

Interactor 2: RBM25 (P49756)
RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7)
Gene: RBM25

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0016607 - nuclear speck
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 225 Hs			1 843
+	Hs
		446541 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		RBM25_HUMAN (1-843): 8.68e-63: 229: 100.00
+	Hs
		61731 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		A6H8W8_HUMAN (398-772): 1.48e-24: 113: 14.10
+	Hs
		441383 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		ITSN2_HUMAN (3-678): 5.19e-14: 78.7: 10.77
+	Hs
		446723 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		PHF3_HUMAN (280-432): 6.42e-20: 98.1: 25.33
+	Hs
		446522 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		CSTF2_HUMAN (78-259): 3.07e-15: 81.8: 16.84
+	Sp
		252608 RU1A_SCHPO (2-225): 2.35e-42: 145: 36.40		US107_SCHPO (89-640): 5.83e-13: 74.8: 16.19
+	Hs
		235918 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		ANR11_HUMAN (156-693): 1.85e-17: 90.1: 14.41
+	Hs
		320999 PTBP3_HUMAN (4-224): 2.96e-13: 70.1: 15.35		MYH10_HUMAN (228-817): 4.57e-14: 78.7: 9.49
+	Hs
		321082 PTBP3_HUMAN (4-224): 2.96e-13: 70.1: 15.35		PLEC_HUMAN (142-787): 2.15e-11: 70.2: 11.30