HitPredict

Interactor 1: RU2B (P08579)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: SNRPB2

Interactor 2: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29884807
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 225 Hs			1 656
+	Hs
		441341 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		446726 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		446593 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		441235 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		212094 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		HTSF1_HUMAN (310-448): 3.35e-28: 122: 20.55
+	Hs
		446526 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		235984 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		1031411 PABP4_HUMAN (148-225): 1.72e-13: 70.9: 19.28		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		516620 PABP1_HUMAN (141-225): 2.1e-13: 70.5: 17.78		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		680441 TIA1_HUMAN (2-160): 1.14e-16: 79.4: 13.04		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		967171 ELAV3_HUMAN (120-224): 1.38e-15: 76.3: 18.18		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		642763 ELAV4_HUMAN (101-224): 3.49e-15: 75.2: 19.38		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		235808 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Mm
		857328 TIA1_MOUSE (2-160): 4.64e-17: 80.5: 14.29		EWS_MOUSE (1-656): 4.67e-42: 163: 94.06
+	Sc
		633980 NAM8_YEAST (1-224): 5.12e-42: 150: 16.09		GBP2_YEAST (343-453): 3.82e-16: 83.2: 24.56
+	Hs
		727085 PTBP2_HUMAN (1-224): 4.63e-16: 78.2: 17.98		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		235735 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		726795 PABP4_HUMAN (148-225): 1.72e-13: 70.9: 19.28		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		516383 PABP1_HUMAN (141-225): 2.1e-13: 70.5: 17.78		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Mm
		882694 HNRPQ_MOUSE (4-224): 1.17e-13: 71.3: 20.00		FUS_MOUSE (66-545): 4.19e-27: 117: 32.08