HitPredict

Interactor 1: RU2B (P08579)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: SNRPB2

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 225 Hs			1 746
+	Hs
		446654 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		235879 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		1031345 PABP4_HUMAN (148-225): 1.72e-13: 70.9: 19.28		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		516536 PABP1_HUMAN (141-225): 2.1e-13: 70.5: 17.78		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		963528 TIAR_HUMAN (143-223): 1.61e-10: 61.7: 26.19		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		446781 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		SETD2_HUMAN (190-732): 2.07e-89: 310: 16.64
+	Hs
		516645 PABP1_HUMAN (141-225): 2.1e-13: 70.5: 17.78		NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82
+	Sc
		810351 NAM8_YEAST (1-224): 5.12e-42: 150: 16.09		SET2_YEAST (470-733): 1.22e-59: 216: 25.56
+	Hs
		236137 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		SET1B_HUMAN (619-732): 1.38e-18: 93.2: 40.52