HitPredict

Interactor 1: RU2B (P08579)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: SNRPB2

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 225 Hs			1 551
+	Mm
		857339 TIA1_MOUSE (2-160): 4.64e-17: 80.5: 14.29		CPSF6_MOUSE (1-520): 4.58e-92: 294: 99.62
+	Hs
		235881 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00
+	Hs
		321092 PTBP3_HUMAN (4-224): 2.96e-13: 70.1: 15.35		CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00
+	Hs
		446705 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Sc
		376895 NAM8_YEAST (1-224): 5.12e-42: 150: 16.09		PABP_YEAST (82-174): 3.01e-12: 71.1: 27.96
+	Hs
		446769 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59
+	Hs
		446785 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		WDR33_HUMAN (180-396): 5.21e-09: 61.5: 24.69
+	Hs
		1020249 ELAV2_HUMAN (128-224): 1.33e-15: 76.3: 19.61		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Zm
		8143 A0A1D6ELH4_MAIZE (5-159): 2.68e-19: 87.9: 18.47		A0A1D6ELH4_MAIZE (60-456): 7.52e-26: 113: 13.55
+	Hs
		235835 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Mm
		665745 TIA1_MOUSE (2-160): 4.64e-17: 80.5: 14.29		PABP1_MOUSE (81-518): 3.65e-24: 108: 16.63
+	Hs
		516484 ELAV2_HUMAN (128-224): 1.33e-15: 76.3: 19.61		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		235683 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		516495 PABP4_HUMAN (148-225): 1.72e-13: 70.9: 19.28		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		516339 PABP1_HUMAN (141-225): 2.1e-13: 70.5: 17.78		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		516689 PABP1_HUMAN (141-225): 2.1e-13: 70.5: 17.78		PABP3_HUMAN (82-518): 1.28e-22: 103: 15.56
+	Hs
		516471 TIAR_HUMAN (143-223): 1.61e-10: 61.7: 26.19		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		963541 TIAR_HUMAN (143-223): 1.61e-10: 61.7: 26.19		LFG1_HUMAN (272-366): 2.55e-09: 61.1: 33.33