HitPredict

Interactor 1: RU2B (P08579)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: SNRPB2

Interactor 2: LSM4 (Q9Y4Z0)
U6 snRNA-associated Sm-like protein LSm4 (Glycine-rich protein) (GRP)
Gene: LSM4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071005 - U2-type precatalytic spliceosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 225 Hs			1 139
+	Hs
		446855 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		LSM4_HUMAN (1-139): 4.8e-47: 150: 100.00
+	Hs
		441257 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		SMD1_HUMAN (1-94): 4.78e-32: 111: 25.26
+	Hs
		441259 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		SMD3_HUMAN (2-108): 2.51e-28: 102: 30.84
+	Hs
		446847 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		LSM2_HUMAN (1-94): 2.68e-36: 121: 28.42
+	Hs
		441255 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		RUXF_HUMAN (3-70): 3.59e-27: 98.2: 33.82
+	Sc
		960463 NAM8_YEAST (1-224): 5.12e-42: 150: 16.09		SMD1_YEAST (1-120): 8.22e-33: 114: 20.55
+	Dm
		795459 SNRPA_DROME (1-225): 1.52e-43: 147: 64.44		SMD1_DROME (1-92): 1.08e-32: 113: 24.73
+	Hs
		446569 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		SMD1_HUMAN (1-94): 4.78e-32: 111: 25.26
+	Dm
		218356 SNRPA_DROME (1-225): 1.52e-43: 147: 64.44		SMD3_DROME (2-112): 4.36e-30: 107: 30.63
+	Sc
		795405 NAM8_YEAST (1-224): 5.12e-42: 150: 16.09		SMD3_YEAST (2-102): 4.51e-28: 100: 33.66
+	Hs
		446571 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		SMD3_HUMAN (2-108): 2.51e-28: 102: 30.84
+	Hs
		446566 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		RUXF_HUMAN (3-70): 3.59e-27: 98.2: 33.82
+	Sp
		145527 GBP2_SCHPO (2-223): 1.7e-14: 73.6: 21.40		LSM4_SCHPO (1-89): 4.18e-35: 119: 60.67
+	Hs
		321257 PTBP3_HUMAN (4-224): 2.96e-13: 70.1: 15.35		LSM2_HUMAN (1-94): 2.68e-36: 121: 28.42
+	Hs
		235785 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		RUXF_HUMAN (3-70): 3.59e-27: 98.2: 33.82