HitPredict

Interactor 1: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 36736316
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1390 Hs			1 135
+	Hs
		119098 MET_HUMAN (1-1390): 0: 1283: 100.00		LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50
+	Hs
		449247 MERTK_HUMAN (1057-1385): 1.56e-67: 249: 40.88		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		165148 PLXB2_HUMAN (365-1012): 1.26e-58: 225: 16.57		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		435502 IGF1R_HUMAN (1084-1337): 2.07e-56: 217: 42.16		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		411281 INSR_HUMAN (1084-1335): 3.87e-55: 213: 42.11		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		449379 PLXA1_HUMAN (461-1020): 8.14e-54: 209: 20.36		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		253449 PLXA2_HUMAN (380-1069): 6.87e-53: 206: 18.27		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		119085 INSR_HUMAN (1084-1335): 3.87e-55: 213: 42.11		LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50
+	Hs
		119558 PLXA1_HUMAN (461-1020): 8.14e-54: 209: 20.36		LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50