HitPredict

Interactor 1: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.608

Property	Details
Experiments	11254878, 16909210
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1390 Hs			1 882
+	Hs
		441427 MET_HUMAN (1-1390): 0: 1283: 100.00		CADH2_HUMAN (28-881): 0: 769: 45.86
+	Hs
		441505 MET_HUMAN (1-1390): 0: 1283: 100.00		DSC3_HUMAN (2-874): 0: 655: 27.92
+	Hs
		580213 EPHA4_HUMAN (555-1389): 3.08e-175: 549: 17.20		CADH2_HUMAN (28-881): 0: 769: 45.86
+	Hs
		580236 EPHA7_HUMAN (587-1389): 6.03e-156: 498: 18.53		CADH2_HUMAN (28-881): 0: 769: 45.86
+	Hs
		872427 EPHA5_HUMAN (579-1346): 3.64e-177: 556: 19.08		DSC2_HUMAN (33-874): 0: 652: 27.88
+	Hs
		872632 EPHA4_HUMAN (555-1389): 3.08e-175: 549: 17.20		DSC2_HUMAN (33-874): 0: 652: 27.88
+	Hs
		971014 EPHA7_HUMAN (587-1389): 6.03e-156: 498: 18.53		DSC2_HUMAN (33-874): 0: 652: 27.88
+	Hs
		580227 TYRO3_HUMAN (1053-1341): 6.19e-65: 240: 41.67		CADH2_HUMAN (28-881): 0: 769: 45.86
+	Hs
		580205 RYK_HUMAN (1078-1334): 2.54e-59: 218: 39.47		CADH2_HUMAN (28-881): 0: 769: 45.86
+	Hs
		987245 TYRO3_HUMAN (1053-1341): 6.19e-65: 240: 41.67		DSC3_HUMAN (2-874): 0: 655: 27.92
+	Hs
		713804 RYK_HUMAN (1078-1334): 2.54e-59: 218: 39.47		DSC3_HUMAN (2-874): 0: 655: 27.92
+	Hs
		713786 RYK_HUMAN (1078-1334): 2.54e-59: 218: 39.47		DSC2_HUMAN (33-874): 0: 652: 27.88
+	Hs
		872602 EPHB4_HUMAN (736-1342): 2.91e-128: 424: 21.72		PCDA8_HUMAN (379-862): 3.62e-64: 235: 16.63
+	Hs
		850513 PLXA3_HUMAN (381-1019): 8.58e-111: 388: 17.82		PCDBF_HUMAN (376-868): 3.69e-69: 246: 14.54
+	Hs
		872598 EPHB4_HUMAN (736-1342): 2.91e-128: 424: 21.72		PCDB3_HUMAN (596-858): 7.97e-16: 84.2: 13.87
+	Hs
		713831 RYK_HUMAN (1078-1334): 2.54e-59: 218: 39.47		DSG4_HUMAN (149-694): 4.56e-78: 276: 34.03
+	Hs
		850512 PLXA3_HUMAN (381-1019): 8.58e-111: 388: 17.82		PCDB3_HUMAN (596-858): 7.97e-16: 84.2: 13.87
+	Hs
		713894 RYK_HUMAN (1078-1334): 2.54e-59: 218: 39.47		PCDB2_HUMAN (432-868): 4.05e-69: 246: 15.17
+	Hs
		702743 RYK_HUMAN (1078-1334): 2.54e-59: 218: 39.47		CADH5_HUMAN (30-511): 8.2e-52: 196: 20.91
+	Hs
		674578 UFO_HUMAN (1078-1333): 5.27e-66: 243: 45.90		PCDB3_HUMAN (596-858): 7.97e-16: 84.2: 13.87