HitPredict

Interactor 1: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: CD44 (P16070)
CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
Gene: CD44

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	28205554, 22897854
Identification Methods	fluorescent resonance energy transfer, cross-linking study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0016477 - cell migration
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1390 Hs			1 742
+	Hs
		555076 FGFR2_HUMAN (1029-1379): 3.01e-105: 355: 33.15		CD44_HUMAN (1-742): 0: 610: 100.00
+	Hs
		555083 UFO_HUMAN (1078-1333): 5.27e-66: 243: 45.90		CD44_HUMAN (1-742): 0: 610: 100.00
+	Hs
		555145 ERBB4_HUMAN (1082-1338): 4.97e-52: 203: 42.75		CD44_HUMAN (1-742): 0: 610: 100.00
+	Rn
		90444 INSR_RAT (1084-1335): 3.22e-52: 204: 40.98		E0X583_RAT (23-123): 4.55e-29: 127: 24.53
+	Rn
		94295 INSR_RAT (1084-1335): 3.22e-52: 204: 40.98		F1LZZ6_RAT (23-123): 4.6e-29: 127: 24.53