Interactor 1: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET
Interactor 2: VAV2 (P52735)
Guanine nucleotide exchange factor VAV2 (VAV-2)
Gene: VAV2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.47 | 1.00 | 0.692 |
The method score is based on:
Property | Details |
---|---|
Experiments | 24728074 |
Identification Methods | pull down, fluorescence polarization spectroscopy |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | C1_1~PK_Tyr_Ser-Thr, PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2 |
Common GO terms | GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0016477 - cell migration |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024