HitPredict

Interactor 1: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: HGFA (Q04756)
Hepatocyte growth factor activator (HGF activator) (HGFA) (EC 3.4.21.-) [Cleaved into: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain]
Gene: HGFAC

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	9537587
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Kringle~PSI, Kringle~Sema
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1390 Hs			1 655
+	Hs
		441530 MET_HUMAN (1-1390): 0: 1283: 100.00		TM11B_HUMAN (392-646): 3.34e-76: 251: 28.52
+	Hs
		341345 MET_HUMAN (1-1390): 0: 1283: 100.00		PLMN_HUMAN (26-648): 2.29e-66: 234: 21.92
+	Hs
		441573 MET_HUMAN (1-1390): 0: 1283: 100.00		TMPS4_HUMAN (265-648): 3.51e-66: 225: 22.86
+	Hs
		177794 MET_HUMAN (1-1390): 0: 1283: 100.00		TMPS2_HUMAN (405-646): 5.22e-37: 146: 35.63
+	Hs
		441419 MET_HUMAN (1-1390): 0: 1283: 100.00		HGF_HUMAN (93-266): 2.31e-09: 62.4: 14.94
+	Hs
		645876 RON_HUMAN (23-1390): 0: 934: 32.70		HGFL_HUMAN (93-348): 7.32e-11: 67.4: 11.83
+	Hs
		428666 EPHA3_HUMAN (584-1379): 1.09e-179: 561: 18.13		TRY1_HUMAN (412-649): 2.39e-70: 230: 33.61
+	Hs
		872716 EPHA4_HUMAN (555-1389): 3.08e-175: 549: 17.20		TMPS4_HUMAN (265-648): 3.51e-66: 225: 22.86
+	Hs
		1072534 EPHA7_HUMAN (587-1389): 6.03e-156: 498: 18.53		TM11B_HUMAN (392-646): 3.34e-76: 251: 28.52
+	Hs
		1072608 EPHA7_HUMAN (587-1389): 6.03e-156: 498: 18.53		TMPS4_HUMAN (265-648): 3.51e-66: 225: 22.86
+	Hs
		872570 EPHB4_HUMAN (736-1342): 2.91e-128: 424: 21.72		TMPSD_HUMAN (270-655): 1.22e-69: 239: 26.09
+	Hs
		872513 EPHB4_HUMAN (736-1342): 2.91e-128: 424: 21.72		TMPS3_HUMAN (270-648): 7.84e-69: 233: 23.39
+	Hs
		872582 EPHB4_HUMAN (736-1342): 2.91e-128: 424: 21.72		TMPS4_HUMAN (265-648): 3.51e-66: 225: 22.86
+	Hs
		850504 PLXA3_HUMAN (381-1019): 8.58e-111: 388: 17.82		TMPS4_HUMAN (265-648): 3.51e-66: 225: 22.86
+	Hs
		409508 EPHB4_HUMAN (736-1342): 2.91e-128: 424: 21.72		HEPS_HUMAN (392-646): 3e-35: 140: 34.20
+	Hs
		177847 PLXA3_HUMAN (381-1019): 8.58e-111: 388: 17.82		TMPS2_HUMAN (405-646): 5.22e-37: 146: 35.63
+	Hs
		165219 PLXB2_HUMAN (365-1012): 1.26e-58: 225: 16.57		TM11B_HUMAN (392-646): 3.34e-76: 251: 28.52
+	Hs
		165175 PLXB2_HUMAN (365-1012): 1.26e-58: 225: 16.57		TMPS3_HUMAN (270-648): 7.84e-69: 233: 23.39
+	Hs
		165259 PLXB2_HUMAN (365-1012): 1.26e-58: 225: 16.57		TMPS4_HUMAN (265-648): 3.51e-66: 225: 22.86
+	Hs
		165123 PLXB2_HUMAN (365-1012): 1.26e-58: 225: 16.57		TMPS2_HUMAN (405-646): 5.22e-37: 146: 35.63