HitPredict

Interactor 1: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24550280
Identification Methods	phage display
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LRR_8~PK_Tyr_Ser-Thr, LRR_8~TIG
Common GO terms	GO:0005886 - plasma membrane GO:0016477 - cell migration GO:0050918 - positive chemotaxis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1390 Hs			1 1630
+	Hs
		665600 EPHB2_HUMAN (597-1389): 7.92e-156: 500: 18.91		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		1049958 EPHA7_HUMAN (587-1389): 6.03e-156: 498: 18.53		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Mm
		555008 MET_MOUSE (1-1381): 0: 1246: 89.57		DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42
+	At
		85369 ERL1_ARATH (522-1388): 0: 580: 13.17		FLS2_ARATH (8-621): 1.42e-111: 385: 21.36
+	At
		85353 ERL1_ARATH (522-1388): 0: 580: 13.17		ERL2_ARATH (1-454): 8.53e-99: 343: 25.16
+	At
		85344 ERL1_ARATH (522-1388): 0: 580: 13.17		ERL1_ARATH (1-381): 6.28e-93: 326: 26.48
+	At
		85352 ERL1_ARATH (522-1388): 0: 580: 13.17		ERECT_ARATH (1-314): 5.22e-72: 264: 24.00
+	At
		1341095 CLV1_ARATH (565-1339): 0: 566: 14.48		BAME2_ARATH (172-820): 9.84e-65: 242: 15.72
+	Gm
		1341216 CLV1B_SOYBN (510-1350): 1.51e-176: 553: 13.84		CLV1B_SOYBN (163-820): 7.04e-63: 236: 14.59
+	At
		85350 ERL1_ARATH (522-1388): 0: 580: 13.17		BAME3_ARATH (1-169): 9.01e-34: 144: 24.58
+	At
		84616 CLV1_ARATH (565-1339): 0: 566: 14.48		RGI3_ARATH (304-435): 9.9e-18: 92.1: 20.95
+	At
		84590 RLK5_ARATH (501-1362): 4.28e-177: 555: 13.77		RGI3_ARATH (304-435): 9.9e-18: 92.1: 20.95
+	Hs
		872433 EPHA5_HUMAN (579-1346): 3.64e-177: 556: 19.08		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		665420 EPHA3_HUMAN (584-1379): 1.09e-179: 561: 18.13		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		872639 EPHA4_HUMAN (555-1389): 3.08e-175: 549: 17.20		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		872473 EPHA5_HUMAN (579-1346): 3.64e-177: 556: 19.08		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	At
		812864 RLK5_ARATH (501-1362): 4.28e-177: 555: 13.77		EMS1_ARATH (373-596): 6.91e-12: 72.8: 10.22
+	Hs
		872694 EPHA4_HUMAN (555-1389): 3.08e-175: 549: 17.20		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		1021499 EPHA7_HUMAN (587-1389): 6.03e-156: 498: 18.53		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		1072577 EPHA7_HUMAN (587-1389): 6.03e-156: 498: 18.53		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06